Renal Pharmacotherapy

Renal Pharmacotherapy

Dosage Adjustment of Medications Eliminated by the Kidneys

Larry K. Golightly, Isaac Teitelbaum, Bonita A. Simendinger, Tyree H. Kiser, Gerard R. Barber

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Description


To promote effectiveness and minimize possible toxicity, the dosage of certain medications must be adjusted in persons with compromised kidney function.  Failure to enjoin appropriate dosage adjustments in patients with abnormal or rapidly changing kidney function continues to lead to reports of drug toxicity involving a broad array of renally eliminated medications.

This updated edition captures nearly 200 new drugs that have been approved by the FDA since the initial publication of Renal Pharmacotherapy. It also covers new evidence that has emerged regarding the need to adjust dosage of certain older medications that are eliminated by the kidneys.  Additionally, it presents new data that are being continuously derived in the areas of patient-specific dose individualization for drugs of all types.

Comprehensive, convenient, and evidence-based, this reference closes several identified knowledge gaps and will continue to be the leading collection of dosage recommendations for patients with compromised kidney function.




Author

Larry K. Golightly:

Larry K. Golightly, PharmD

Clinical Research Pharmacist

University of Colorado Hospital

Aurora, CO 80045

larry.golightly@uchealth.org

 

Isaac Teitelbaum, MD, FACP

Professor of Medicine

Renal Medicine and Hypertension Section, Division of General Internal Medicine

University of Colorado School of Medicine and

Director, Home Dialysis Program

University of Colorado Hospital

Aurora, CO 80045

isaac.teitelbaum@cuanschutz.edu

 

Bonita A. Simendinger, PharmD, BCPS

P&T Formulary Compliance Specialist

University of Colorado Hospital

Aurora, CO 80045

bonita.simendinger@uchealth.org

 

Tyree H. Kiser, PharmD, BCPS, FCCP, FCCM

Professor, Department of Clinical Pharmacy

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and

Critical Care Pharmacy Specialist

University of Colorado Hospital

Aurora, CO 80045

ty.kiser@cuanschutz.edu

 

Gerard R. Barber, RPh, MPH, FASHP

Clinical Assistant Professor, Department of Clinical Pharmacy

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences

Aurora, CO 80045

gerard.barber@cuanschutz.edu

 

Nancy M. Stolpman, PharmD, PhD

Associate Clinical Professor

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and

Lead Director of Pharmacy

UCHealth

Aurora, CO 80045

nancy.stolpman@uchealth.org


|||

Larry K. Golightly, PharmD

Clinical Research Pharmacist

University of Colorado Hospital

Aurora, CO 80045

larry.golightly@uchealth.org

 

Isaac Teitelbaum, MD, FACP

Professor of Medicine

Renal Medicine and Hypertension Section, Division of General Internal Medicine

University of Colorado School of Medicine and

Director, Home Dialysis Program

University of Colorado Hospital

Aurora, CO 80045

isaac.teitelbaum@cuanschutz.edu

 

Bonita A. Simendinger, PharmD, BCPS

P&T Formulary Compliance Specialist

University of Colorado Hospital

Aurora, CO 80045

bonita.simendinger@uchealth.org

 

Tyree H. Kiser, PharmD, BCPS, FCCP, FCCM

Professor, Department of Clinical Pharmacy

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and

Critical Care Pharmacy Specialist

University of Colorado Hospital

Aurora, CO 80045

ty.kiser@cuanschutz.edu

 

Gerard R. Barber, RPh, MPH, FASHP

Clinical Assistant Professor, Department of Clinical Pharmacy

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences

Aurora, CO 80045

gerard.barber@cuanschutz.edu

 

Nancy M. Stolpman, PharmD, PhD

Associate Clinical Professor

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and

Lead Director of Pharmacy

UCHealth

Aurora, CO 80045

nancy.stolpman@uchealth.org


|||

Larry K. Golightly, PharmD

Clinical Research Pharmacist

University of Colorado Hospital

Aurora, CO 80045

larry.golightly@uchealth.org

 

Isaac Teitelbaum, MD, FACP

Professor of Medicine

Renal Medicine and Hypertension Section, Division of General Internal Medicine

University of Colorado School of Medicine and

Director, Home Dialysis Program

University of Colorado Hospital

Aurora, CO 80045

isaac.teitelbaum@cuanschutz.edu

 

Bonita A. Simendinger, PharmD, BCPS

P&T Formulary Compliance Specialist

University of Colorado Hospital

Aurora, CO 80045

bonita.simendinger@uchealth.org

 

Tyree H. Kiser, PharmD, BCPS, FCCP, FCCM

Professor, Department of Clinical Pharmacy

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and

Critical Care Pharmacy Specialist

University of Colorado Hospital

Aurora, CO 80045

ty.kiser@cuanschutz.edu

 

Gerard R. Barber, RPh, MPH, FASHP

Clinical Assistant Professor, Department of Clinical Pharmacy

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences

Aurora, CO 80045

gerard.barber@cuanschutz.edu

 

Nancy M. Stolpman, PharmD, PhD

Associate Clinical Professor

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and

Lead Director of Pharmacy

UCHealth

Aurora, CO 80045

nancy.stolpman@uchealth.org


|||

Larry K. Golightly, PharmD

Clinical Research Pharmacist

University of Colorado Hospital

Aurora, CO 80045

larry.golightly@uchealth.org

 

Isaac Teitelbaum, MD, FACP

Professor of Medicine

Renal Medicine and Hypertension Section, Division of General Internal Medicine

University of Colorado School of Medicine and

Director, Home Dialysis Program

University of Colorado Hospital

Aurora, CO 80045

isaac.teitelbaum@cuanschutz.edu

 

Bonita A. Simendinger, PharmD, BCPS

P&T Formulary Compliance Specialist

University of Colorado Hospital

Aurora, CO 80045

bonita.simendinger@uchealth.org

 

Tyree H. Kiser, PharmD, BCPS, FCCP, FCCM

Professor, Department of Clinical Pharmacy

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and

Critical Care Pharmacy Specialist

University of Colorado Hospital

Aurora, CO 80045

ty.kiser@cuanschutz.edu

 

Gerard R. Barber, RPh, MPH, FASHP

Clinical Assistant Professor, Department of Clinical Pharmacy

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences

Aurora, CO 80045

gerard.barber@cuanschutz.edu

 

Nancy M. Stolpman, PharmD, PhD

Associate Clinical Professor

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and

Lead Director of Pharmacy

UCHealth

Aurora, CO 80045

nancy.stolpman@uchealth.org


|||

Larry K. Golightly, PharmD

Clinical Research Pharmacist

University of Colorado Hospital

Aurora, CO 80045

larry.golightly@uchealth.org

 

Isaac Teitelbaum, MD, FACP

Professor of Medicine

Renal Medicine and Hypertension Section, Division of General Internal Medicine

University of Colorado School of Medicine and

Director, Home Dialysis Program

University of Colorado Hospital

Aurora, CO 80045

isaac.teitelbaum@cuanschutz.edu

 

Bonita A. Simendinger, PharmD, BCPS

P&T Formulary Compliance Specialist

University of Colorado Hospital

Aurora, CO 80045

bonita.simendinger@uchealth.org

 

Tyree H. Kiser, PharmD, BCPS, FCCP, FCCM

Professor, Department of Clinical Pharmacy

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and

Critical Care Pharmacy Specialist

University of Colorado Hospital

Aurora, CO 80045

ty.kiser@cuanschutz.edu

 

Gerard R. Barber, RPh, MPH, FASHP

Clinical Assistant Professor, Department of Clinical Pharmacy

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences

Aurora, CO 80045

gerard.barber@cuanschutz.edu

 

Nancy M. Stolpman, PharmD, PhD

Associate Clinical Professor

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and

Lead Director of Pharmacy

UCHealth

Aurora, CO 80045

nancy.stolpman@uchealth.org


|||

Larry K. Golightly, PharmD

Clinical Research Pharmacist

University of Colorado Hospital

Aurora, CO 80045

larry.golightly@uchealth.org

 

Isaac Teitelbaum, MD, FACP

Professor of Medicine

Renal Medicine and Hypertension Section, Division of General Internal Medicine

University of Colorado School of Medicine and

Director, Home Dialysis Program

University of Colorado Hospital

Aurora, CO 80045

isaac.teitelbaum@cuanschutz.edu

 

Bonita A. Simendinger, PharmD, BCPS

P&T Formulary Compliance Specialist

University of Colorado Hospital

Aurora, CO 80045

bonita.simendinger@uchealth.org

 

Tyree H. Kiser, PharmD, BCPS, FCCP, FCCM

Professor, Department of Clinical Pharmacy

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and

Critical Care Pharmacy Specialist

University of Colorado Hospital

Aurora, CO 80045

ty.kiser@cuanschutz.edu

 

Gerard R. Barber, RPh, MPH, FASHP

Clinical Assistant Professor, Department of Clinical Pharmacy

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences

Aurora, CO 80045

gerard.barber@cuanschutz.edu

 

Nancy M. Stolpman, PharmD, PhD

Associate Clinical Professor

University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences and

Lead Director of Pharmacy

UCHealth

Aurora, CO 80045

nancy.stolpman@uchealth.org


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